Girish J Kotwal
University of Massachusetts
USA
Title: Prompt management of ageing based on disease risk analysis of genotype and lifestyle can contribute to Longevity and improved health
Biography
Biography: Girish J Kotwal
Abstract
Background: At the beginning of this century, the sequence of the entire human genome has been determined, Subsequently the influence of single nucleotide polymorphisms (SNP) has been studied and the risk for diseases like Alzheimer’s Disease, type 2 diabetes, Parkinson’s disease that occur in later years of life can be predicted by alleles that predisposes a person to ageing related diseases. rnrnApproach: DNA is isolated from Saliva and SNP analysis is performed for several specific diseases related genes. The level of risk for predisposition to certain diseases which have been previously established was then determined and placed in the context of phenotypic findings.rnrnResults: SNP analysis of over 50 genes in a father and son pair was conducted and the results will be presented.rnrnConclusion: Genes play a key role in Longevity and in gaining insights on how life style changes can overcome gene defects and understanding the interplay of genes, one can better manage Ageing and reduce cost of hospitalization and falls that occur due to defective vision or balancern
